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nexusstc/Nanoparticulate drug delivery/f01d0831c87cf3fb59c65368195fe393.pdf
Nanoparticulate Drug Delivery: Perspectives on the Transition from Laboratory to Market (Woodhead Publishing Series in Biomedicine) 🔍
Vandana Patravale, Prajakta Dandekar and Ratnesh Jain Woodhead Publishing Limited, Woodhead publishing series in biomedicine -- no. 17, Woodhead Publishing series in biomedicine -- no. 17., Cambridge, U.K, Philadelphia, PA, England, 2012
英语 [en] · PDF · 3.7MB · 2012 · 📘 非小说类图书 · 🚀/duxiu/lgli/lgrs/nexusstc/zlib · Save
描述
Nanoparticles offer distinct advantages in pharmaceutical products by protecting the drug, targeting it to the diseased tissue and providing release at the desired rate. Implementation of this strategy in actual products, however, has proved challenging. Nanoparticles must perform several specific tasks in the body: they need to exhibit sufficient encapsulation of the drug, possess requisite material characteristics to release the drug at the desired rate and have a long enough circulation in order to accumulate at the target in necessary quantities. The challenges in designing nanoparticles have given rise to the field of nanomedicine, which seeks to formulate nanoparticles to meet the therapeutic objective. With this book, the authors provide a summary of the past efforts, current status and future directions of nanomedicine. They begin by explaining the design goals of nanoparticles to improve drug solubility and targeting and discuss different types of nanoparticles. Subsequent chapters include a thorough examination of various routes of administration, including oral, transdermal, pulmonary and intravenous. Latter parts cover nanotoxicology, regulatory aspects in clinical trials and concludes with an overview of case studies about nano-systems in the marketplace.
备用文件名
lgli/Nanoparticulate drug delivery.pdf
备用文件名
lgrsnf/Nanoparticulate drug delivery.pdf
备用文件名
zlib/Medicine/Vandana Patravale, Prajakta Dandekar, Ratnesh Jain/Nanoparticulate drug delivery: Perspectives on the transition from laboratory to market_2086732.pdf
备选标题
NANOPARTICULATE DRUG DELIVERY:PERSPECTIVES ON THE TRANSITION FROM THE LABORATORY TO MARKET
备选作者
Patravale, Vandana, Dandekar, Prajakta, Jain, Ratnesh
备用出版商
Biohealthcare Publishing (Oxford) Limited
备用出版商
Chartridge Books Oxford
备用版本
Woodhead Publishing Series in Biomedicine, no. 17, Oxford, 2012
备用版本
United Kingdom and Ireland, United Kingdom
备用版本
Elsevier Ltd., Oxford, 2012
元数据中的注释
0
元数据中的注释
lg932862
元数据中的注释
{"edition":"1","isbns":["1907568980","9781907568985"],"last_page":244,"publisher":"Woodhead Publishing Limited","series":"Woodhead Publishing Series in Biomedicine"}
元数据中的注释
Includes bibliographical references and index.
备用描述
Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments.<br><br><ul><li>Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation</li><li>Provides an overview of new application areas, including RNA interference</li><li>Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector</li></ul>
备用描述
Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments. Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulationProvides an overview of new application areas, including RNA interferenceOutlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector
备用描述
Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems, operating at scales of billionths of a metre, from laboratory into a commercially viable sector.
开源日期
2013-07-10
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