It has been well recognized that following an ischemic insult many nerve cells of the brain are not killed outright, but may suffer a "delayed neuronal death" or even recover. This led to the concept of "maturation phenomenon" with its main implication that the maturation of ischemic lesions may provide a "window of opportunity" i.e. a period of time when the injury to neuronal elements is still reversible, and during which an application of proper therapeutic measures might be successful. The symposium on Maturation Phenomenon in Cerebral Ischemia was the first international meeting focussed primarily on this subject and the resulting publication contains presentations and discussionsby prominent researchers engaged in this field. This book should stimulate further research on potential of brain tissue for recovery, and particularly with regard to a functional recovery of neurons suffering from chronic ischemic injury.
Erscheinungsdatum: 14.09.1992

lgrsnf/A:\Springer\bok%3A978-3-642-77134-7.pdf

nexusstc/Maturation Phenomenon in Cerebral Ischemia: Proceedings of the Satellite Symposium of the XIth International Congress of Neuropathology Tokyo, September 11–12, 1990/e92df52e32aff5b590b303ae8474d7d1.pdf

zlib/Medicine/U. Ito, T. Yamaguchi, H. Tomita, O. Tone (auth.), Umeo Ito M.D., T. Kirino M.D., T. Kuroiwa M.D., Igor Klatzo M.D. (eds.)/Maturation Phenomenon in Cerebral Ischemia: Proceedings of the Satellite Symposium of the XIth International Congress of Neuropathology Tokyo, September 11–12, 1990_2267461.pdf

Ito, U. (umeo), International Congress Of Neuropathology (11th : 1990 : Kyoto, Japan)

Umeo Ito; International Congress of Neuropathology

Spektrum Akademischer Verlag. in Springer-Verlag GmbH

Springer Spektrum. in Springer-Verlag GmbH

Steinkopff. in Springer-Verlag GmbH

Springer London, Limited

Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest, 1992

Springer Nature, Berlin, Heidelberg, 2012

Berlin, New York, Germany, 1992

Germany, Germany

January 1992

lg1098501

{"edition":"1","isbns":["3540548718","3642771343","9783540548713","9783642771347"],"last_page":208,"publisher":"Springer"}

Includes bibliographical references and indexes.

Front Matter....Pages I-XVI
Maturation of Ischemic Injuries Observed in Mongolian Gerbils: Introductory Remarks....Pages 1-13
Maturational Death of the Neuron in Ischemic Brain Injury....Pages 15-22
Reorganization in the Gerbil Hippocampus After Ischemia-Induced Delayed Neuronal Death: Fate of Parvalbumin-Containing Neurons....Pages 23-31
Changes in Hippocampal Ultrastructure After Ischemia with Long Survival Times....Pages 33-39
Possible Role of Intracellular Calcium Translocation in the Maturation of Ischemic Damage....Pages 41-47
Reversibility of Damage to Rat Cerebellar Purkinje Cells Following Ischemia....Pages 49-56
Neuropathological Changes in Remote Areas After Focal Cerebral Ischemia....Pages 57-64
Dynamics of Late Neuronal Changes in Global Cerebral Ischemia....Pages 65-74
Role of Neuroexcitation in Maturation of Postischemic and Posttraumatic Injury....Pages 75-86
Pharmacological Contradictions in Neurotoxicity of Excitatory Amino Acids as a Cause of Ischemic Injuries....Pages 87-94
Involvement of Excitatory Transmitter Systems in Ischemia-Induced Damage to CA1 Pyramidal Cells, Dentate Hilus Neurons, and Purkinje’s Cells....Pages 95-105
Importance of Postischemic Neurotransmission in Delayed Neuronal Death....Pages 107-119
Role of Altered Gene Expression in Development of Neuronal Changes After Ischemia....Pages 121-128
Protein Synthesis and Calcium Uptake Following Complete Cerebral Ischemia of Rat Brain....Pages 129-138
Ischemic Neuronal Injury Modified by Basic Fibroblast Growth Factor....Pages 139-149
Simultaneous Mapping of Superoxide Free Radicals, Vascular Permeability, and Energy Metabolism in Forebrain Ischemic Lesions by a New Technique....Pages 151-159
Carotid Artery Back Pressure and Postischemic Hyperthermia in the Gerbil: Factors Influencing the Delayed Neuronal Death of the Hippocampal CA1 Sector....Pages 161-168
Cerebral Ischemia in Adult and Young Mongolian Gerbils: Delayed Changes in Monoamines....Pages 169-177
Effect of Recurrent Ischemia on the Rate of Brain Function Recovery in Monkeys....Pages 179-184
Residual Oxygen Metabolism in Completely Ischemic Tissue of the Cat Brain: A Polarographic Method for Measuring Flow and Metabolism in the Microregion....Pages 185-193
Synopsis of the Round Table Discussion....Pages 195-199
Back Matter....Pages 201-208

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