It was the genius of Gordon Murray in Toronto that introduced the use of allografts into cardiac surgery in the 1950s. Soon after this on opposite sides ofthe world, Sir Brian Barratt-Boyes in Auckland, New Zealand, and Mr. Donald Ross in London, undertook to use allografts for the replacement of diseased aortic valves. Since that time the global interest in allografts has been patchy, episodic, and without a con sensus. Nonetheless, for the last 20 years at least three groups in the world have steadfastly pursued the development of new and relevant information concerning the use of allograft valves in humans. These are the centres of Sir Brian Barratt Boyes, Mr. Donald Ross, and Mark O'Brien in Brisbane. More recently, talented investigators, including Drs. Yankah, Yacoub, and others, have been developing information concerning the immunological aspects of the use of allografts, as well as their clinical use. No doubt, at present, cardiac valve allografts of one sort or another are the devices of choice for conduits and have an important place in the surgery of aortic valve replacement. Even so, in the mind of this writer at least, the future usefulness of allografts for the replacement of diseased cardiac valves and conduits between a ventricle and the pulmonary artery, remains problematic, and depends upon improvements in other devices for this purpose and upon improve ments that may be made in preparing and using allografts.
Erscheinungsdatum: 21.12.2011

lgrsnf/A:\Springer\bok%3A978-3-642-72420-6.pdf

nexusstc/Cardiac Valve Allografts 1962–1987: Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Subsitutes/c6f08dd0a29b0648c4b9e1ef6f8ccd2b.pdf

zlib/Medicine/D. N. Ross M.D. (auth.), A. Charles Yankah M.D., Roland Hetzer M.D., D. Craig Miller M.D., Donald Ross M.D., Jane Somerville M.D., Magdi H. Yacoub M.D. (eds.)/Cardiac Valve Allografts 1962–1987: Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Subsitutes_2266364.pdf

Spektrum Akademischer Verlag. in Springer-Verlag GmbH

Steinkopff. in Springer-Verlag GmbH

Steinkopff-Verlag Darmstadt

Steinkopff, Dietrich

Dietrich Steinkopff

Springer Nature, Heidelberg, 2012

Heidelberg, 1988

Germany, Germany

1, 2011

lg1097404

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Front Matter....Pages I-XVI
Evolution of the biological concept in cardiac surgery: A Pilgrim’s Progress....Pages 1-11
Allogeneic valve procurement in cardiac transplantation....Pages 13-16
Antibiotic sterilisation in the preparation of homovital homograft valves: Is it necessary?....Pages 17-21
Procurement and viability of cardiac valve allografts....Pages 23-26
Cryobiology of tissues....Pages 27-34
Cryopreservation of aortic valve homografts....Pages 35-36
Factors affecting the viability of cryopreserved allograft heart valves....Pages 37-42
Endothelial and fibroblast viability assays for tissue allografts....Pages 43-48
Discussion....Pages 49-51
Contribution for discussion: Problems of homograft procurement....Pages 52-54
Contribution for discussion: Heart valve procurement in Berlin....Pages 55-57
Basic principles of transplantation immunology....Pages 59-64
Cryopreserved and fresh valved aortic homograft conduits in a chronic sheep model: Haemodynamic, angiographic and histological comparisons....Pages 65-68
Homograft valve calcification: Evidence for an immunological influence....Pages 69-74
Pathology of human explanted aortic valve homografts: A comparative morphological study with porcine aortic valve explants....Pages 75-76
Antigenicity and fate of cellular components of heart valve allografts....Pages 77-87
Immunohistopathology of cardiac valve allograft explants....Pages 89-94
Applications and limitations of histocompatibility in clinical cardiac valve allograft surgery....Pages 95-102
Discussion....Pages 103-106
The anatomy of the outflow tracts of the heart and of aortic and pulmonary allografts....Pages 107-111
Selection of allograft valve size....Pages 113-123
“Fresh” free-hand, non-viable allografts for aortic valve replacement: Operative techniques and 15-year results....Pages 125-140
Modified techniques for subcoronary insertion of allografts....Pages 141-147
Allograft aortic root replacement....Pages 149-155
Extended aortic root replacement in 12 patients with complex left ventricular outflow tract obstruction....Pages 157-165
Aortic root replacement with a cardiac allograft: The infected aortic root....Pages 167-171
Indications and surgical technique of aortic valve replacement with the autologous pulmonary valve....Pages 173-180
The morphology of tricuspid atresia, pulmonary atresia and truncus arteriosus....Pages 181-184
Population-based requirements for allograft surgery in children....Pages 185-187
The pulmonary allograft for right ventricular outflow tract reconstruction....Pages 189-193
Pulmonary valve allograft reconstruction of the right ventricular outflow tract....Pages 195-203
Technique of inlay allografts into the RVOT to prevent pulmonary insufficiency....Pages 205-213
Allografts in the treatment of absent pulmonary valve syndrome and complex tetralogy of Fallot....Pages 215-219
Technique of allograft repair of tetralogy of Fallot with pulmonary atresia....Pages 221-222
The use of aortic allografts in the primary repair of truncus arteriosus in early infancy and replacement of previous conduits....Pages 223-227
Allografts in the Rastelli procedure: Techniques....Pages 229-235
Allograft conduit for Fontan procedure....Pages 237-247
Late results of homograft function used for right ventricular outflow obstruction....Pages 249-259
Pulmonary autografts, viable and non-viable aortic homografts in the subcoronary position: A comparative study....Pages 261-264
Long-term results of antibiotic-treated aortic allografts in subcoronary position....Pages 265-271
Survival of aortic allografts containing living cells....Pages 273-280
Short-term results after allograft transplantation in the pulmonary position following previous repair of tetralogy of Fallot....Pages 281-290
Intermediate-term results of cryopreserved allograft and xenograft valved ventricle to pulmonary artery conduits....Pages 291-299
Functional evaluation of allografts by non-invasive techniques....Pages 301-309
Cryopreserved viable allograft aortic valves....Pages 311-321
Short-term follow-up of cryopreserved allograft valves and valved conduits from the CryoLife clinical registry....Pages 323-332
Discussion....Pages 333-343
Contribution for discussion: A mathematical model of aortic valve vibration....Pages 345-346
25 Years’ clinical experience of allograft surgery — A time for reflection....Pages 347-369
Panel Discussion....Pages 371-384
Summary....Pages 385-390
Closing Remarks....Pages 391-391
Back Matter....Pages 392-395

2013-12-12