The period between 1950 and 1980 were the golden It also provides unique insights into how pathological years of transmission electron microscopy and pro- processes affect cell organization. duced a plethora of new information on the structure of This information is vital to current work in which cells that was coupled to and followed by biochemical the emphasis is on integrating approaches from p- and functional studies. TEM was king and each micro- teomics, molecular biology, molecular imaging and graph of a new object produced new information that physiology, and pathology to understand cell functions led to new insights on cell and tissue organization and and derangements in disease. In this current era, there is their functions. The quality of data represented by the a growing tendency to substitute modern light mic- images of cells and tissues had been perfected to a very scopic techniques for electron microscopy because it is high level by the great microscopists of the era including less technically demanding and is more readily available Palade, Porter, Fawcett, Sjostrand, Rhodin and many to researchers. This atlas reminds us that the infor- others. At present, the images that we see in leading tion obtained by electron microscopy is invaluable and journals for the most part do not reach the same techni- has no substitute.

Margit Pavelka; Jürgen Roth

Pavelka, Margit , 1945-

Springer-Verlag GmbH

1 edition, March 22, 2005

1st ed, New York, 2005

Austria, Austria

Wien, 2002

1, 2004

This Atlas Of Functional Ultrastructure Provides Not Only A Detailed Insight Into The Complex Structure And Organization Of Cells And Tissues But Also Into Specific Functions Fulfilled By The Various Cellular Organelles And The Dynamics Of The Different Processes Inside Cells. The Large Collection Of Electron Micrographs, Together With Those From Immunoelectron Microscopy, Is Complemented By Thorough Explanatory Texts And Schemes. Emphasis Was Placed On An Integrated View Of Structure And Function To Show That Subcellular Organelles Provide The Structural Foundation For Fundamental Processes Of Living Organisms. Specialized Cell Types Form The Various Tissues, And Principles Of Tissue Organization Are Presented. Under Various Conditions Of Disease, Characteristic Structural Alterations May Occur Which Are Illustrated With Examples Thus Providing A Valuable Source Of Information For Scientists And Students Of Medicine And Biological Sciences, Particularly Of Histology, Cell An. Introduction : Structural Organisation Of A Mammalian Cell -- The Nucleus -- Architecture Of The Cell Nucleus -- Cytochemical Detection Of Ribonucleoproteins -- Nuclear Lamina -- Detection Of Sites Of Dna Replication And Of Interphase Chromosome Domains -- Nucleolus -- Changes Of The Nucleolar Architecture -- Detection Of Sites Of Rna Synthesis -- Nuclear Pore Complexes -- Nuclear Pore Complexes : Structural Changes As Monitored By Time-lapse Atomic Force Microscopy -- Mitosis And Cell Division -- Apoptosis -- Viral Inclusions -- The Cytoplasm : The Secretory System -- Secretory Pathway Of Pancreatic Acinar Cells -- Ribosomes, Rough Endoplasmic Reticulum -- Nuclear Envelope And Rough Endoplasmic Reticulum. Margit Pavelka, Jürgen Roth. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.

All eukaryotic cells present qualitatively a very similar structural organisation that can vary quantitatively depending on their degree of differentiation and specialisation as well as functional state.

2025-10-04