This book is a result of the First Conference on Lipoxygenases, held at Malta, May 17th-2l st, 1997. The goal was very ambitious: having lipoxygenases as a focus for distant and diverse experimental approaches, we brought together scientists to discuss and build a consensus on the biological role of lipoxygenases. Although still fuzzy in many details, the Malta conference has shown that a unifying view on lipoxygenases is finally taking shape, and that the experimental evidence of links and conjugations among events OCCUf­ ing from cell membranes to intracellular compartments and the nucleus is becoming in­ creasingly convincing. The editors are deeply grateful to Hospital for Sick Children, Toronto, Free Univer­ sity Berlin, NOAA Sea Grant College Program (U. S. A. ), Schering, Berlin (F. R. G. ), and Cayman Chemicals, Ann Arbor, Michigan (U. S. A. ), for their generous financial support, which was crucial in making the conference a scientific success. The conference received financial support from a number of additional sponsors, and we express our gratitude to Abbott Labs (U. S. A. ), Air Malta (Malta), Ass. Int. Cancer Res. (U. K. ), Biometra (F. R. G. ), Bayer AG (F. R. G. ), IBL Co. (F. R. G. ), Merck Frosst (Canada), Perkin Elmer (F. R. G. ), Scotia Pharmaceuticals (Canada), Searle (U. S. A. ), SPI Chemicals (France), and TOPCRO (Austria).

scihub/10.1007/978-1-4615-4861-4_fm.pdf

zlib/no-category/Nigam, Santosh; Pace-Asciak, Cecil R/[Advances in Experimental Medicine and Biology] Lipoxygenases and their Metabolites Volume 447 || || Front_matter_53610420.pdf

Lipoxygenases and Their Metabolites : Biological Functions

Tankred Schewe, Cecil R. Pace-Asciak, Santosh Nigam (auth.), Santosh Nigam, Cecil R. Pace-Asciak (eds.)

Springer Nature

Springer US

Advances in Experimental Medicine and Biology Ser, New York, NY, 1999

Advances in experimental medicine and biology, 447, Boston, MA, 1999

United States, United States of America

Springer Nature, New York, NY, 2012

1, 20121206

sm21211814

sm23152129

This book is a compendium of recent knowledge relating to the biology, pathophysiology, pharmacology, and genetics of lipoxygenases and their products, edited as proceedings of an international congress held in Malta in the summer of 1997. It represents state-of-the-art insight into the above topics. The aim of the book is to broaden the existing knowledge on lipoxygenases and metabolites and to identify directions for future research, which, in our opinion, is accomplished by the contribution of recognized experts in the field. Papers based on the congress lectures are gathered together here under three general headings: (i) enzymology, molecular biology and biological functions of mammalian lipoxygenases, (ii) metabolic regulation of lipoxygenases; lipoxygenase inhibitors, (iii) products of the lipoxygenase pathways and their receptors, which present enticing and forward-looking presentations.
It is hoped that the novel structural and mechanistic insights encapsulated in this book will conspire to engender new exciting research, whose results will coalesce into next conferences of this kind at regular intervals

2013-11-24