Vascular diseases, particularly atherosclerosis, are the most frequent and critical underlying fatal disorders in the industrialized world. Cardiovascular deaths are the leading cause of death in the Western world. Although cancer or malignant neoplasms recently have topped the list of causes of deaths in Japan, cardiovascular and cerebrovascular diseases bring about more deaths than cancer if they are reclassified into a unified category of diseases of the vascular system. The National Cardiovascular Center was established by the Ministry of Health and Welfare of Japan to combat cardiovascular and cerebrovascular diseases. Since the Center was opened, we have continued to support basic and clinical sturlies of cardiovascular and cerebrovascular diseases within as weil as outside the Center. Clinical studies that we have supported in modern diagnostic and therapeutic measures against cardio- and cerebrovascular diseases have made remarkable advances in recent years, especially in medical imaging technology including CT and MRI, and in interventional measures including balloon angioplasty and other catheter-based treatments. We are proud of the significant improvement in the overall survival rate and the quality of life of patients suffering from vascular disorders. However, there are still many essential difficulties remaining in the diagnosis and treatment of vascular disorders. Such difficulties necessitate further fundamental studies not only from the practical aspect but also from the integrated perspectives of medicine, biology, and engineering.
Erscheinungsdatum: 03.10.2013

lgrsnf/A:\compressed\10.1007%2F978-4-431-67921-9.pdf

nexusstc/Clinical Application of Computational Mechanics to the Cardiovascular System/412f8e32717f908956363a1a045db05f.pdf

scihub/10.1007/978-4-431-67921-9.pdf

zlib/Medicine/Takami Yamaguchi (auth.), Takami Yamaguchi M.D., Ph.D. (eds.)/Clinical Application of Computational Mechanics to the Cardiovascular System_2114692.pdf

Springer London, Limited

Springer Japan Co., Ltd.

Springer Nature, Tokyo, 2013

Jun 29, 2013

Japan, Japan

Tokyo, 2000

lg960791

{"edition":"1","isbns":["4431679219","4431679898","9784431679219","9784431679899"],"last_page":288,"publisher":"Springer Japan"}

Front Matter....Pages I-XXXII
Front Matter....Pages 1-1
Computational Mechanical Model Studies in the Cardiovascular System....Pages 3-18
Inelastic Constitutive Models of Blood Vessels in Physiological Conditions....Pages 19-28
Stress and Strain Analyses of Blood Vessels in Physiological and Pathological Conditions....Pages 29-38
Development of Interactive Modeling System for the Computational Biomechanics Simulation using Medical Imaging Data....Pages 39-42
A Modeling System of 3-Dimensional Blood Vessel Configuration for CFD Analysis....Pages 43-46
Front Matter....Pages 47-47
Computational Analysis for Mechanical Functions of Left Ventricle....Pages 49-58
Automated Tracking of Tagged Magnetic Resonance Image for Assessment of Regional Cardiac Wall Function....Pages 59-69
Error Estimation and Smoothing for Regional Deformation Analysis of the Heart with Tagged Magnetic Resonance Images....Pages 70-75
Deformation Analysis of Human Left Ventricular Wall Using Magnetic Resonance Tagging Technique....Pages 76-82
Motion and Strain Analyses of Left Ventricular Wall Using Optical Flow....Pages 83-92
Intraventricular blood flow analysis using robust CFD models....Pages 93-96
Front Matter....Pages 97-97
Computational fluid mechanics of the blood flow in an aortic vessel with realistic geometry....Pages 99-117
Numerical Simulation and Experiment of Pulsatile Flow in Modeled Aortic Arch....Pages 118-131
Flow Simulation of the Aortic Arch —Effect of the 3D Distortion on Flows in the Ordinary Helix Circular Tube—....Pages 132-135
Computational Fluid Mechanics of the Vortical Flow in Blood Vessel....Pages 136-156
Computational Study on LDL Transfer from Flowing Blood to Arterial Walls....Pages 157-173
Numerical Simulation of Co-operative Regulation in the Cerebral Microvascular Arcadal Network....Pages 174-185
Computational Fluid Dynamic Simulation of the Flow through Venous Valve....Pages 186-189
Front Matter....Pages 191-191
A High-performance Computation Method for Simulation of Cardiac Excitation Propagation using a Supercomputer....Pages 193-204
Simulated Electrocardiogram of Spiral Wave Reentry in a Mathematical Ventricular Model....Pages 205-216
Front Matter....Pages 191-191
Computational Analysis and Visualization of Spiral Wave Reentry in a Virtual Heart Model....Pages 217-241
Simulation of platelet adhesion using a discrete element method....Pages 242-245
Computational Fluid Dynamics as a Tool to Develop the Artificial Heart....Pages 246-257
Three-Dimensional Image Processing and Motion Analysis of the Heart Using Radionuclide Medical Images....Pages 258-268
The Modeling of the Heart and the Aortic Arch applying Differential Geometrical Method and Simulation of Blood Flow....Pages 269-272
Orientation Response of Stress Fibers in Cultured Cells under Biaxial Cyclic Stretch: Hypothesis and Theoretical Prediction....Pages 273-282
Back Matter....Pages 283-288

The term "computational biomechanics" describes the approach taken in a 3-year project promoted by the National Cardiovascular Center of Japan to integrate fluid and solid mechanics in studies of the heart and vascular system. The goal was to create a new, comprehensive methodology in cardiovascular research, including both radiological and electrophysiological studies to achieve the most comprehensive view. This book compiles reports of the work conducted by leading researchers in biomechanics using a full array of cutting-edge technology - from the supercomputer in the National Cardiovascular Center to individual PCs. The book stresses application rather than development of theory, thus appealing to a wide audience ranging from researchers without extensive backgrounds in computation, to graduate students and clinical practitioners. Enhanced with color illustrations, the book is a valuable resource in biomedical engineering

2013-08-01