Over the past fifty years, the case-control method, and to a lesser extent its case-based variants, have become the most important tools for the investigator of health problems. The case control method is the study of persons with the disease and a suitable control group of persons who do not have the disease. The book helps readers address a number of general and specific questions dealing with the case-control and other case-based methods, including questions of how to design and implement a case-control study that minimizes biases, how to analyze the data to appropriately deal with confounding variables and help identify reactions, and how to interpret data and present the results from a case-control study.

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nexusstc/The Case-Control Method/3ae3dc5419224c17608eddd16992504a.pdf

zlib/Biology and other natural sciences/Haroutune Armenian M.D./The Case-Control Method: Design and Applications (Monographs in Epidemilogy and Biostatistics, Volume 38)_969765.pdf

The Case-Control Method: Design and Applications (Monographs in Epidemiology and Biostatistics, 38)

The Case-Control Method: Design and Applications (Monographs in Evolutionary Biology)

Haroutune K. Armenian

Oxford Institute for Energy Studies

German Historical Institute London

Monographs in epidemiology and biostatistics, New York ; Oxford, ©2009

Monographs in epidemiology and biostatistics, v. 38, Oxford, 2009

United Kingdom and Ireland, United Kingdom

Oxford University Press USA, Oxford, 2009

New York, New York State, 2009

1 edition, September 2006

New York, 2009-05-14

до 2011-01

lg545364

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Includes bibliographical references.

The case-control method, and to a lesser extent its case-based variants, have become a most important tool in the armamentarium of today's investigator of health problems. This book addresses a number of general and specific questions dealing with the case-control and other case-based methods, including how to design and implement a case-control study that minimizes biases; how to analyze the data to deal appropriately with confounding and to help identify interactions; how to interpret data from a case-control study; and how to use the method in a variety of problem solving situations. The book provides an exposition of the uses of a study of individual cases as well as case series in epidemiology. It describes the development of the comparative method as a basis for decision making in the health professions. The first part of the book deals with issues of design of the case control and other case based methods such as the case-crossover and case-cohort studies. In this section of the book several issues of design and analysis of case-control studies are presented within a framework for developing an information base for decision making in research and in health care. The second part of the book has a focus on the applications of the method. These include the use of case-control studies in outbreak investigations as well as other acute events such as disasters, the use of the method in health care and health services evaluation, and its use in genetic epidemiology as well as other applications

From case investigation to the case-control method : information for decision making
Problem investigation and inferences using the case-control method
Avoiding bias in case and control selection
Avoiding information bias in exposure assessment
Alternative case based designs
Analysis of case-control data
Applications : outbreak investigation
Genetic epidemiology for case-based designs
Applications : evaluation
Applications : evaluation of screening programs
Other applications.

This title helps readers address a number of general and specific questions dealing with the case-control and other case-based methods, including questions of how to design and implement a case-control study that minimizes biases, how to analyze the data to appropriately deal with confounding variables and more

2011-06-04